Jesuit Missions responds to emergencies around the world, often working with the Xavier Network, a group of European Jesuit NGOs. In the past few years Jesuit Missions has helped with food relief following the crisis in Zimbabwe in 2008 and helped rebuild areas of Haiti following the devastating Earthquake.

In 2013 Jesuit Missions launched an emergency appeal following Typhoon Haiyan in the Philippines and provides regular support internationally for Jesuit Refugee Services.